7-Deaza-2',3'-dideoxyadenosine

CAS: 40627-30-3

Ref. 3D-ND00041

Product Information

• Name: 7-Deaza-2',3'-dideoxyadenosine
• Synonyms: 2',3'-dideoxytubercidin7-Deaza-2',3'-dideoxy-D-adenosine
• Brand: Biosynth
• Description: 7-Deaza-2',3'-dideoxyadenosine (7DDAD) is a nucleoside analogue that has been used as an immunodeficiency agent. This drug inhibits the replication of the human immunodeficiency virus (HIV). 7DDAD is a prodrug that is converted to adenosine after it enters the cell, and this conversion prevents DNA synthesis. The effective dose of 7DDAD is 50 mg/kg in rats, but this dose may vary depending on the technique used. 7DDAD has been shown to be effective in vitro against HIV-1 and HIV-2 isolates, and it can also be used to treat cytomegalovirus infections. In addition, 7DDAD has been shown to inhibit the growth of various types of cancer cells in vitro.

Chemical properties

• Molecular weight: 234.26 g/mol
• Formula: C₁₁H₁₄N₄O₂
• Purity: Min. 98 Area-%
• Color/Form: Powder