2'-Deoxycytidine HCl

CAS: 3992-42-5

Ref. 3D-ND02591

Product Information

• Name: 2'-Deoxycytidine HCl
• Synonyms: 2'-Deoxy-D-cytidine HCl, 2'-Deoxycytidine Hydrochloride (1:1), 2-Deoxycytidine HCl, 2-Deoxycytidine monohydrochloride, 2-Deoycytidine hydrochloride, 4-amino-1-(2-deoxypentofuranosyl)pyrimidin-2(1H)-one, 4-amino-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one hydrochloride, Cytidine, 2′-deoxy-, hydrochloride (1:1), Cytidine, 2′-deoxy-, monohydrochloride, Cytosine deoxyriboside hydrochloride~1-(2-Deoxy-beta-D-ribofuranosyl)cytosine hydrochloride, Deoxycytidine hydrochloride, NSC 83251

Description

2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.

• Brand: Biosynth

Chemical properties

• Molecular weight: 263.68 g/mol
• Formula: C₉H₁₃N₃O₄·HCl
• Purity: Min. 98 Area-%
• Color/Form: White Powder