3'-Deoxy-5-methyluridine

CAS: 7084-29-9

Ref. 3D-ND02776

Product Information

• Name: 3'-Deoxy-5-methyluridine
• Synonyms: 5-Methyl-3'-deoxyuridine3'-Deoxy-5-methyl-D-uridine5'-Methyl-3'-deoxyuridine
• Brand: Biosynth
• Description: 3'-Deoxy-5-methyluridine (3'-DMAU) is a synthetic nucleoside that is used in the treatment of viral infections. 3'-DMAU has antiviral and anticancer activity, and it has been used to synthesize DNA for genetic engineering. It has shown promising results in the treatment of HIV as well as in the prevention of cancer metastasis. 3'-DMAU inhibits DNA synthesis by binding to the enzyme RNA polymerase, which blocks its interaction with ribonucleosides, thus inhibiting RNA synthesis. In addition, 3'-DMAU causes cell death by inhibiting protein synthesis. The drug is activated by phosphorylation to form 5'-triphosphate and 5'-diphosphate derivatives, which inhibit DNA and RNA synthesis at multiple sites within the cell.

Chemical properties

• Molecular weight: 242.23 g/mol
• Formula: C₁₀H₁₄N₂O₅
• Purity: Min. 95%
• Color/Form: Powder