7-Deaza-2'-deoxyguanosine

CAS: 86392-75-8

Ref. 3D-ND02887

Product Information

• Name: 7-Deaza-2'-deoxyguanosine
• Synonyms: 7-Deaza-2'-deoxy-D-guanosine
• Brand: Biosynth
• Description: 7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.

Chemical properties

• Molecular weight: 266.26 g/mol
• Formula: C₁₁H₁₄N₄O₄
• Purity: Min. 95%
• Color/Form: White Powder