7-Deaza-2'-deoxyadenosine

CAS: 60129-59-1

Ref. 3D-ND02936

Product Information

• Name: 7-Deaza-2'-deoxyadenosine
• Synonyms: 2-Deoxytubercidin7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine7-Deaza-2'-deoxy-D-adenosine, (2R,3S,5R)-5-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol, 2′-Deoxy-7-deazaadenosine, 2′-Deoxytubercidin, 2′-Deoxyxylotubercidin, 7-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7-Deaza-deoxyadenosine, 7-Deazadeoxyadenosine, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, 7H-Pyrrolo[2,3-d]pyrimidine, 4-amino-7-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, Deoxytubercidin, 7H-Pyrrolo[2,3-d]pyrimidine, 4-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-, 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2-deoxy-β-D-erythro-pentofuranosyl)-

Description

7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.

• Brand: Biosynth

Chemical properties

• Molecular weight: 250.26 g/mol
• Formula: C₁₁H₁₄N₄O₃
• Purity: Min. 98 Area-%
• Color/Form: White Powder