5'-O-DMT-thymidine

CAS: 40615-39-2

Ref. 3D-ND03361

Product Information

• Name: 5'-O-DMT-thymidine
• Synonyms: 5'-O-DMT-D-thymidine, 1-{(3xi)-5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-beta-D-glycero-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, 5'-Dimethoxytrityl Thymidine, 5'-O-(4,4'-Dimethoxytrityl)-2'-Deoxythymidine, 5'-O-(4,4'-Dimethoxytrityl)Thymidine, 5'-O-(Dimethoxytrityl)-Thymidine, 5'-O-Dimethoxytrityl-Deoxythymidine, 5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxythymidine, 5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine, 5’-O-[Bis(4-Methoxyphenyl)Phenylmethyl]-Thymidin, 5′-O-(Di-p-methoxytrityl)thymidine, 5′-O-(p,p′-Dimethoxytrityl)thymidine, 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]thymidine, DMT-dT, Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, Thymidine, 5′-O-[α,α-bis(p-methoxyphenyl)benzyl]-

Description

5’-O-DMT-thymidine is also known as 5’-O-(4,4’-dimethoxytrityl)thymidine. It is a key deoxynucleoside building block that is protected with a dimethoxytrityl group in the 5-O-position of the deoxy-ribose moiety, leaving the 3-hydroxyl free for modification. It is used a convenient starting point for nucleotide synthesis. 5’-O-DMT-thymidine can be converted into 3’-O-phosphoramidite derivatives for oligonucleotide synthesis. Additionally, 5’-O-DMT-thymidine can be converted into more stable 1-N-protected derivatives.

• Brand: Biosynth

Chemical properties

• Molecular weight: 544.6 g/mol
• Formula: C₃₁H₃₂N₂O₇
• Purity: Min. 98 Area-%
• Color/Form: White Powder