2'-Deoxy-5-iodouridine

CAS: 54-42-2

Ref. 3D-ND05147

Product Information

• Name: 2'-Deoxy-5-iodouridine
• Synonyms: 1-(2-Deoxy-b-D-ribofuranosyl)-5-iodouracilIdoxuridineDendrid2'-Deoxy-5-iodo-D-uridine5-Iodo-2'-deoxyuridine, 1-(2-Dehydroxy-β-D-ribofuranosyl)-5-iodouracil, 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-iodouracil, 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil, 1-(2-deoxy-beta-D-threo-pentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione, 1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione, 1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]-5-iodopyrimidine-2,4(1H,3H)-dione, 2'-Desoxy-5-iodouridine, 2-Deoxy-5-iodouridine, 5-Iodo-2'-Deoxy-D-Uridine, 5-Iodo-2'-desoxyuridine, 5-Iodo-deoxyuridine, 5-Iododeoxyuridine, 5-Iodouracil deoxyriboside, 5Iudr, Allergan 211, Dendrid, Emanil, Herpe-Gel, Herpesil, Herpidu, Herplex, IDU, Idexur, Idoxene, Idoxuridin, Idoxuridina, Idoxuridine, Idu Oculos, Iducher, Idulea, Idur, Iduridin, Iododeoxyuridine, Iudr, Joddeoxiuridin, Kerecid, Nsc 39661, Ophthalmadine, Skf 14287, Stoxil, Stoxip, Synmiol, Uridine, 2'-deoxy-5-iodo-, Virudox, 5-Iodo-2'-deoxyuridine

Description

2'-Deoxy-5-iodouridine (IDU) is a nucleoside that inhibits viral replication by inhibiting the synthesis of viral DNA. IDU has been shown to be a potent inhibitor of murine sarcoma virus and human immunodeficiency virus (HIV). IDU also has inhibitory properties on axonal growth, which may be due to its ability to inhibit DNA polymerase II. 2'-Deoxy-5-iodouridine is biocompatible, non-toxic, and can be used in high concentrations without any acute toxicities.

• Brand: Biosynth

Chemical properties

• Molecular weight: 354.1 g/mol
• Formula: C₉H₁₁IN₂O₅
• Purity: Min. 95%
• Color/Form: Powder