7-Deazaguanosine

CAS: 62160-23-0

Ref. 3D-ND05752

Product Information

• Name: 7-Deazaguanosine
• Synonyms: 2-Amino-7-b-D-ribofuranosyl[3,2-d]pyrimidin-4-one7-Deaza-9-(b-D-ribofuranosyl)guanine7-Deaza-D-guanosine
• Brand: Biosynth
• Description: 7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses.

Chemical properties

• Molecular weight: 282.26 g/mol
• Formula: C₁₁H₁₄N₄O₅
• Purity: Min. 95%
• Color/Form: Off-White Powder