5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside

CAS: 53-85-0

Ref. 3D-ND06701

Product Information

• Name: 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside
• Synonyms: DBR5,6-Dichlorobenzimidazole riboside, 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5,6-dichlorobenzimidazole, 1H-Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5,6-Dichloro-1-(β-<span class="text-smallcaps">D</span>-ribofuranosyl)benzimidazole, 5,6-Dichloro-1-b-D-ribofuranosylbenzimidazole, 5,6-Dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole, 5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside, 5,6-Dichlorobenzimidazole 1-β-<span class="text-smallcaps">D</span>-ribofuranoside, 5,6-Dichlororibofuranosylbenzimidazole, 5,6-dichloro-1-(beta-D-ribofuranosyl)-1H-benzimidazole, 5,6-dichloro-1-[(2xi)-beta-D-threo-pentofuranosyl]-1H-benzimidazole, 5,6-dichloro-1-pentofuranosyl-1H-benzimidazole, Benzimidazole, 5,6-dichloro-1-<span class="text-smallcaps">D</span>-ribofuranosyl-, Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, NSC 401575, Nqz-002, 5,6-Dichloro-1-β-D-ribofuranosyl-1H-benzimidazole, 5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole, 1H-Benzimidazole, 5,6-dichloro-1-β-D-ribofuranosyl-, Benzimidazole, 5,6-dichloro-1-D-ribofuranosyl-, Benzimidazole, 5,6-dichloro-1-β-D-ribofuranosyl-

Description

5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside is a chemical compound that has been shown to be neurotoxic in vitro. It has significant cytotoxicity against human leukemia cells (HL60) and induces neuronal death. This drug also inhibits the production of neurotrophic factors, which are vital for the normal development of neurons. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside inhibits transcriptional regulation of genes that encode for receptors and enzymes. The compound is chemically stable and does not degrade easily by hydrolysis or oxidation. It can bind to polymerase chain reaction (PCR) primers and inhibit DNA synthesis. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside also affects cell nuclei by inhibiting DNA synthesis and enzyme activities.

• Brand: Biosynth

Chemical properties

• Molecular weight: 319.15 g/mol
• Formula: C₁₂H₁₂Cl₂N₂O₄
• Purity: Min. 98 Area-%
• Color/Form: White Powder