2'-Deoxy-5-ethyluridine

CAS: 15176-29-1

Ref. 3D-ND08006

Product Information

• Name: 2'-Deoxy-5-ethyluridine
• Synonyms: Edoxudine2'-Deoxy-5-ethyl-D-uridine5-Ethyl-2'-deoxyuridine, 1-(2-deoxypentofuranosyl)-5-ethylpyrimidine-2,4(1H,3H)-dione, 2'-Deoxy-5-Ethyluridine, 5-Ethyl-1-(2′-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)uracil, 5-Ethyldeoxyuridine, 5-ethyl-1-[4-hydroxy-3-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione, Aedurid, Edoxudine, Epoxudine, Orf 15817, Rwj 15817, Uridine, 2′-deoxy-5-ethyl-, β-5-Ethyl-2′-deoxyuridine, β-5-Ethyldeoxyuridine

Description

2'-Deoxy-5-ethyluridine is a nucleoside analog that is used in cancer gene therapy. It is an analog of the natural pyrimidine base uracil and inhibits RNA synthesis by competing with natural nucleosides for incorporation into the growing RNA chain. 2'-Deoxy-5-ethyluridine is cytotoxic to cervical cancer cells, inhibiting cell growth and proliferation at inhibitory doses of 0.1 μM. This drug has also been shown to have synergistic effects with other drugs such as trifluoroacetic acid, monoclonal antibody, tissue culture, glycosidic bond, biological properties, cancer tissues, and polymerase chain reaction (PCR).

• Brand: Biosynth

Chemical properties

• Molecular weight: 256.26 g/mol
• Formula: C₁₁H₁₆N₂O₅
• Purity: Min. 95%
• Color/Form: Powder