3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
Ref. 3D-ND08486
| 1g | 1,179.00 € | ||
| 100mg | 338.00 € | ||
| 250mg | 460.00 € | ||
| 500mg | 712.00 € |
Product Information
- 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-uridine3',5'-Di-O-benzoyl-2'-fluoro-2'-deoxyuridine
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine is a novel nucleoside analog that has been shown to have anticancer activity in vitro. The compound is a monophosphate, which is synthesized from 2'-deoxyuridine and benzoyl chloride. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine was found to have antiviral activity against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). It also inhibited the production of HIV in human lymphocytes. This nucleoside analog can be activated by phosphorylation at the 5' position to form a diphosphate, which inhibits DNA synthesis by incorporating into the growing DNA chain and preventing the movement of RNA polymerase along the template strand.
Chemical properties
Technical inquiry about: 3D-ND08486 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
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