7-Deaza-7-iodoadenosine

CAS: 24386-93-4

Ref. 3D-ND09248

Product Information

• Name: 7-Deaza-7-iodoadenosine
• Synonyms: 7-Iodotubercidin7-Deaza-7-iodo-D-adenosineITU, 4-Amino-5-iodo-7-β-<span class="text-smallcaps">D</span>-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine, 4-Amino-5-iodo-7-β-<span class="text-smallcaps">D</span>-ribofuranosylpyrrolo[2,3-d]pyrimidine, 5-Iodo-7-β-<span class="text-smallcaps">D</span>-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 7-Iodo-7-Deaza-adenosine, 7-Iodo-7-deazaadenosine, 7-Iodotubercidin, 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 5-iodo-7-beta-D-ribofuranosyl-, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 7H-Pyrrolo[2,3-d]pyrimidine, 4-amino-5-iodo-7-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Nqz-020, Nsc 113939, 7H-Pyrrolo[2,3-d]pyrimidine, 4-amino-5-iodo-7-β-D-ribofuranosyl-, 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 4-Amino-5-iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-β-D-ribofuranosyl-

Description

7-Deaza-7-iodoadenosine is a nucleotide that has been used in experiments to assess the levels of adenosine, a dinucleotide phosphate that is involved in many cellular functions. 7-deaza-7-iodoadenosine has been shown to inhibit locomotor activity in rats and cyclase activity in 3T3-L1 preadipocytes. It also inhibits the release of inflammatory proteins from polymorphonuclear leucocytes and angiogenesis (formation of new blood vessels) in liver cells. Although this nucleotide has not been extensively studied, it has been proposed as an antiinflammatory agent because it inhibits protein synthesis and downregulates proinflammatory proteins.

• Brand: Biosynth

Chemical properties

• Molecular weight: 392.15 g/mol
• Formula: C₁₁H₁₃IN₄O₄
• Purity: Min. 95%