Product Information
Name:2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine
Brand:Biosynth
Description:2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is a nucleoside that has antiviral and anticancer effects. It can be used as an activator for phosphoramidites and as a precursor for the synthesis of other nucleosides. 2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is synthesized from 2,4,6-triisopropylbenzenesulfonyl chloride and 5-(N,N-dimethylamino)valeronitrile in the presence of triethylamine and potassium carbonate in acetonitrile with subsequent purification by silica gel chromatography. The resulting compound is then converted to its diphosphate form by treatment with dithiothreitol in dimethylformamide. This product has been shown to inhibit DNA replication and
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Chemical properties
Molecular weight:590.36 g/mol
Formula:C25H23IN2O7
Purity:Min. 95%
Technical inquiry about: 2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine
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