Product Information
Name:2'-Deoxy-2'-fluorocytidine-5'-monophosphate
Synonyms:
- 2'- Deoxy- 2'- fluoro-5'- cytidylic acid
Brand:Biosynth
Description:2'-Deoxy-2'-fluorocytidine-5'-monophosphate (2F-dFMP) is a synthetic nucleoside that is used in the treatment of cancer and as an antiviral agent. 2F-dFMP inhibits DNA synthesis by inhibiting DNA polymerase, which is needed for replication of the cell's genetic material. It also has anti-HIV activity and can be used to treat HIV infection. 2F-dFMP is phosphorylated to 2'-deoxy-2'-fluorocytidine 5'-triphosphate (2F-dCTP), which then competes with natural nucleotides for incorporation into DNA and RNA. This drug binds to the enzyme thymidylate synthase, preventing the formation of thymine monophosphate from erythronic acid.
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Chemical properties
Molecular weight:325.19 g/mol
Formula:C9H13FN3O7P
Purity:Min. 95%
Technical inquiry about: 2'-Deoxy-2'-fluorocytidine-5'-monophosphate
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