3',5'-Di-O-acetylthymidine

CAS: 6979-97-1

Ref. 3D-ND145913

Product Information

• Name: 3',5'-Di-O-acetylthymidine
• Synonyms: Thymidine 3',5'-diacetate, 1-(3,5-di-O-acetyl-2-deoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 3',5'-di-O-acetylthymidine, 3′,5′-Di-O-acetylthymidine, 3′,5′-Diacetyl-5-methyl-2′-deoxyuridine, 3′,5′-Diacetylthymidine, Di-O-acetylthymidine, NSC 526766, NSC 67672, Thymidine, 3′,5′-diacetate

Description

3',5'-Di-O-acetylthymidine is a pyrimidine nucleoside that has antibacterial activity. It is an anomer of thymidine, which makes it a hydroxymethylated analog of thymine. It can be used in the preparation of uridine for the treatment of human immunodeficiency virus type 1 (HIV-1) infection and to study the mechanism of action of this nucleoside on HIV-1 replication. 3',5'-Di-O-acetylthymidine binds to the ribose moiety of pyrimidines and inhibits bacterial growth by inhibiting DNA synthesis. This compound also inhibits the growth of staphylococcus that are resistant to penicillin. The chemical structure of 3',5'-Di-O-acetylthymidine can be modified with different acetic acid substituents to produce other pyrimidine nucleosides with different antibacterial properties, such as 4-

• Brand: Biosynth

Chemical properties

• Molecular weight: 326.3 g/mol
• Formula: C₁₄H₁₈N₂O₇
• Purity: Min. 95%
• Color/Form: Powder