7-Deaza-2'-C-ethynyladenosine

CAS: 1044589-82-3

Ref. 3D-ND15347

Product Information

• Name: 7-Deaza-2'-C-ethynyladenosine
• Brand: Biosynth
• Description: 7-Deaza-2'-C-ethynyladenosine (7DAA) is a research inhibitor that is classified as a polymerase inhibitor. It binds to the active site of the viral NS5B polymerase and inhibits RNA synthesis, which leads to virus replication. 7DAA has shown activity against hepatitis B virus (HBV) and hepatitis C virus (HCV). It also shows multifunctional properties in its inhibition of HBV genotypes A1, A3, and D1. In addition, 7DAA interacts with the RNA binding site on HCV polymerase protein and prevents binding of the viral RNA genome to this site. 7DAA also inhibits HIV replication by preventing assembly of the reverse transcriptase enzyme complex at an early stage.

Chemical properties

• Molecular weight: 290.27 g/mol
• Formula: C₁₃H₁₄N₄O₄
• Purity: Min. 95%
• Color/Form: Powder