7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution

CAS: 101515-08-6

Ref. 3D-ND157324

Product Information

• Name: 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
• Synonyms: 7-Deaza-dGTP.Na, 2'-Deoxy-7-deazaguanosine triphosphate, 2'-Deoxy-7-deaza-GTP, 7-Deaza-2'-deoxyguanosine triphosphate, 7-Deaza-2'-dgtp, C7-Gdtp, 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-7-(2-deoxy-5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-erythro-pentofuranosyl)-1,7-dihydro-, 2-amino-7-[2-deoxy-5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-beta-D-erythro-pentofuranosyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

Description

7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease and

• Brand: Biosynth

Chemical properties

• Molecular weight: 506.19 g/mol
• Formula: C₁₁H₁₇N₄O₁₃P₃·xNa
• Purity: Min. 95%