N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester
CAS: 840506-29-8
Ref. 3D-ND158438
1mg | 194.00 € | ||
2mg | 310.00 € | ||
5mg | 436.00 € | ||
10mg | 647.00 € | ||
25mg | 986.00 € |
Product Information
- N- (2'- Deoxy- 2'
- 2'- difluoro- P- phenyl- 5'- cytidylyl) -L- alanine phenylmethyl esterAcelarin
N-(2'-Deoxy-2',2'-difluorocytidine-5'-P-phenyl-phosphate) L-alanine benzyl ester (DFCP) is an anti-cancer compound that was developed to target leukemic stem cells, which are resistant to traditional chemotherapy drugs. DFCP inhibits the formation of uridine nucleotides, which are required for DNA synthesis and cell proliferation. DFCP has been shown to have a high therapeutic index in animal studies, with low toxicity and low side effects. In vitro experiments have demonstrated that this drug can inhibit the growth of solid tumours and plasma concentration-time curve data in mice show that it is able to reduce metastatic pancreatic cancer.
Chemical properties
Technical inquiry about: 3D-ND158438 N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester
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