Product Information
Name:2'-Deoxy-N7-methylguanosine
Synonyms:
- 2'-Deoxy-7,8-dihydro-7-methylguanosine
Brand:Biosynth
Description:2'-Deoxy-N7-methylguanosine is a hydrogenolysis product of guanosine. It can be synthesized in four steps from glycosyl chloride, glycosylamine, and methyl iodide. The catalytic hydrogenolysis of 2'-deoxy-N7-methylguanosine with Raney Ni gives the corresponding 6-amino derivative. Hydrolysis of this amino group converts it to a nucleoside. This nucleoside has been shown to hydrolyze with half-life of about 1 hour at pH 8.5 and 37°C. The hydrolysis of purines by 2'-deoxy-N7-methylguanosine is inhibited by adenosine analogues like 2',3'-dideoxyadenosine and 3',4'-dideoxyadenosine.
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Chemical properties
Molecular weight:283.28 g/mol
Formula:C11H17N5O4
Purity:Min. 95%
Technical inquiry about: 2'-Deoxy-N7-methylguanosine
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