3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
CAS:
Ref. 3D-ND22463
1g
1,366.00€
50mg
303.00€
100mg
303.00€
250mg
460.00€
500mg
798.00€
Product Information
Name:3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
Synonyms:
- 2'-Deoxy-5-fluoro-uridine 3',5'-bis(4-chlorobenzoate)3,5-Di-O-p-chlorobenzoyl floxuridine
Brand:Biosynth
Description:3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine is a nucleoside derivative that has antiviral activity. It is synthesized by the condensation of 2,3,5-trihydroxybenzoic acid with 3'-chloro-5'-fluoroacetophenone in the presence of pyridine and triethylamine. The nucleoside has been shown to be an effective inhibitor of HIV replication in vitro. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine also inhibits DNA synthesis in human lymphocytes at concentrations of 5 μM or less. This compound can be used as an activator for DNA polymerases and phosphoramidites for DNA synthesis.
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Chemical properties
Molecular weight:523.29 g/mol
Formula:C23H17Cl2FN2O7
Purity:Min. 95%
Technical inquiry about: 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
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