7-Deaza-2'-deoxy-O6-methylguanosine

Ref. 3D-ND31362

Product Information

• Name: 7-Deaza-2'-deoxy-O6-methylguanosine
• Brand: Biosynth
• Description: 7-Deaza-2'-deoxy-O6-methylguanosine is a novel nucleoside phosphoramidite that is the first of its kind to have been shown to be an antiviral agent. It is also anticancerous and stimulates diphosphate synthesis. 7-Deaza-2'-deoxy-O6-methylguanosine is a highly reactive nucleoside phosphoramidite that reacts with DNA in the same manner as deoxyribonucleotides. The monophosphate form of this compound has been shown to be anticancerous and stimulate diphosphate synthesis. This novel compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in vitro.

Chemical properties

• Molecular weight: 280.28 g/mol
• Formula: C₁₂H₁₆N₄O₄
• Purity: Min. 95%
• InChI: InChI=1S/C12H16N4O4/c1-19-11-6-2-3-16(10(6)14-12(13)15-11)9-4-7(18)8(5-17)20-9/h2-3,7-9,17-18H,4-5H2,1H3,(H2,13,14,15)/t7?,8-,9-/m1/s1
• InChI key: InChIKey=FWGROSMSLLFCAQ-CFCGPWAMSA-N
• SMILES: COc1nc(N)nc2c1ccn2[C@H]1CC(O)[C@@H](CO)O1