2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution

CAS: 93939-70-9

Ref. 3D-ND32077

Product Information

• Name: 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution
• Synonyms: ddATP
• Brand: Biosynth

Description

2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a novel antiviral nucleoside that has the potential to be used in the treatment of various viral infections. It is synthesized from 2',3'-dideoxyadenosine monophosphate and lithium salt, and has been shown to have high antiviral activity against DNA viruses such as herpes simplex virus and adenovirus. It also inhibits the replication of RNA viruses such as influenza A virus, vesicular stomatitis virus, and measles virus. 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a modified nucleoside that is phosphoramidite activated with a group at the 2' position on the ribose sugar. The phosphate group can be removed by hydrolysis or enzymatic catalysis, which leaves behind an unsaturated sugar moiety. This leads to an increased rate of incorporation into

Chemical properties

• Molecular weight: 498.91 g/mol
• Formula: C₁₀H₁₂N₅O₁₁P₃·4Li
• Purity: Min. 95%
• Color/Form: Powder