3-Deaza-2'-Deoxyadenosine

CAS: 78582-17-9

Ref. 3D-ND57491

Product Information

• Name: 3-Deaza-2'-Deoxyadenosine
• Brand: Biosynth
• Description: 3-Deaza-2'-Deoxyadenosine is a nucleoside analog that is synthesized from 2'-deoxyadenosine. It has been shown to be more potent than natural adenosine in inhibiting the activity of certain RNA polymerases. 3-Deaza-2'-Deoxyadenosine inhibits RNA synthesis by binding to the ribose moiety of the ribonucleotide, which prevents the formation of an enzyme-substrate complex and thus blocks chain elongation. This compound is also able to inhibit DNA synthesis by binding to the deoxyribose moiety of DNA and preventing DNA polymerase from adding nucleotides to the growing strand. 3-Deaza-2'-Deoxyadenosine has been shown to have antiviral activity against influenza virus and herpes simplex virus type 1 (HSV) in vitro.

Chemical properties

• Molecular weight: 250.25 g/mol
• Formula: C₁₁H₁₄N₄O₃
• Purity: Min. 95%