Product Information
- 5'-Dfma
- Adenosine, 5'-C-fluoro-5'-S-methyl-5'-thio-, (5'R)-
- (5R)-5'-C-fluoro-5'-S-methyl-5'-thioadenosine
5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine is an analogue of adenosine that has inhibitory activities on the biosynthetic pathway of polyamines. It has been shown to have a cytostatic effect on murine leukemia cells in vitro. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine inhibits the production of polyamines by interfering with the enzyme responsible for their biosynthesis, ornithine decarboxylase. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine also inhibits the growth of murine leukemia cells and other leukemia cell lines, including L1210 and MM1.
Chemical properties
Technical inquiry about: 3D-ND87794 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine
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