Product Information
OTS514 is a polymeric molecule that has been shown to have tumor-suppressive and anti-proliferative effects in cancer cells. OTS514 is able to induce autophagy, a process of cellular self-digestion that eliminates the abnormal cell mTOR protein. This drug also inhibits the expression of the leukocyte antigen (HLA) and blocks the G1/S phase transition. OTS514 can be used for treating patients with cervical cancer and other cancers. In vitro studies have shown that OTS514 induces apoptosis in cancer cells by inhibiting proteasome activity and inducing caspase activation. It also inhibits the growth factor epidermal growth factor, which leads to reduced angiogenesis and tumor progression.
Chemical properties
Technical inquiry about: 3D-NDC54063 OTS514
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