Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate

CAS: 149771-09-5

Ref. 3D-NE57446

Product Information

• Name: Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate
• Brand: Biosynth

Description

Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is a small molecule that is a potent inhibitor of diacylglycerol acyltransferase. The compound has been shown to be an efficient inhibitor of this enzyme, which is involved in the synthesis of diacylglycerol. Diacylglycerol acyltransferase catalyzes the transfer of an acyl group from an acyl-carrier protein (ACP) to glycerol 3-phosphate, forming lysophosphatidic acid and releasing CoA. The inhibition of this enzyme leads to drastically reduced levels of diacylglycerol, which may have implications for the treatment of metabolic syndrome and diabetes.

Chemical properties

• Molecular weight: 235.16 g/mol
• Formula: C₈H₈F₃N₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H8F3N3O2/c1-2-16-6(15)4-3-13-7(12)14-5(4)8(9,10)11/h3H,2H2,1H3,(H2,12,13,14)
• InChI key: InChIKey=OUACXMUEZBQRBJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cnc(N)nc1C(F)(F)F