Cefozopran hydrochloride

CAS: 113981-44-5

Ref. 3D-NEA98144

Product Information

• Name: Cefozopran hydrochloride
• Synonyms: (6R,7R)-7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-(methoxyimino)acetamido]-3-(imidazo[1,2-b]pyridazinio-1-ylmethyl)-3-cephem-4-carboxylate hydrochloride, (6R,7R)-7-[[(2E)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride, 1,2,4-Thiadiazole, imidazo[1,2-b]pyridazinium deriv., 1-{[(6R,7R)-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1H-imidazo[1,2-b]pyridazin-4-ium chloride, Cefozopran HCl, Cefozopran monohydrochloride, Firstcin, Imidazo[1,2-b]pyridazinium, 1-[[(6R,7R)-7-[[(2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride, Imidazo[1,2-b]pyridazinium, 1-[[(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride (1:1), Imidazo[1,2-b]pyridazinium, 1-[[7-[[(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, chloride, [6R-[6α,7β(Z)]]-, SCE-2787.HCl, [6R-[6alpha,7beta(Z)]]-1-[[7-[[(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1H-imidazo[1,2-b]pyridazinium chloride

Description

Cefozopran hydrochloride is a prodrug of cefozopran that is converted to its active form in the body. Cefozopran hydrochloride is used for the treatment of chronic pulmonary infections, specifically those caused by infectious diseases or autoimmune diseases. The drug may also be used for the prevention of bacterial endocarditis in patients who have had a dental procedure. Cefozopran hydrochloride is administered as an injection and has a plasma concentration-time curve that peaks between 1-2 hours after administration. Cefozopran hydrochloride has chemical stability at room temperature, but not at a higher temperature of 37 degrees Celsius. It also has good chemical stability in human serum, which makes it useful for intravenous administration.

• Brand: Biosynth

Chemical properties

• Molecular weight: 551.99 g/mol
• Formula: C₁₉H₁₈ClN₉O₅S₂
• Purity: Min. 95%