5-Fluorouridine-5'-triphosphate sodium salt
CAS: 3828-96-4
Ref. 3D-NF32079
| 25mg | 1,134.00 € | ||
| 50mg | 1,620.00 € | ||
| 100mg | 2,399.00 € |
Product Information
5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.
Chemical properties
Technical inquiry about: 3D-NF32079 5-Fluorouridine-5'-triphosphate sodium salt
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