7-Fluoro-L-tryptophan
CAS: 138514-97-3
Ref. 3D-NFA51497
| 1g | 729.00 € | ||
| 2g | 1,047.00 € | ||
| 10mg | 63.00 € | ||
| 50mg | 148.00 € | ||
| 250mg | 430.00 € |
Product Information
7-Fluoro-L-tryptophan is a fluorinated analog of L-tryptophan. Fluorine substitution for hydrogen in the phenyl ring of the molecule increases the photophysical, biological and fluorogenic properties of 7-fluoro-L-tryptophan. It has been shown to have higher potency than L-tryptophan in both clinical and preclinical studies and can be used as a positron emission tomography radiotracer. The method of synthesis involves reacting 7-fluoroindole with tertiary amines. This synthetic procedure is more difficult than that for L-tryptophan, but yields a more pure product. The subunits are synthesized by recombinant microbial fermentation using Escherichia coli bacteria strains such as BL21 (DE3) pLysS or BL21 (DE3) pLysE.
Chemical properties
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