Pasakbumin B
CAS: 138809-10-6
Ref. 3D-NFA80910
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- Spiro[2H-1,11c-(epoxymethano)phenanthro[10,1-bc]pyran-3(3aH),2'-oxirane],picras-3-ene-2,16-dione deriv.
- (+)-Pasakbumin B
Pasakbumin B is a quassinoid that has been shown to reduce blood pressure and promote cancer cell death. Pasakbumin B has been shown to induce apoptosis in mcf-7 cells through the activation of the caspase cascade, which is an intracellular signaling pathway involved in programmed cell death. This compound was found to increase the expression of pro-apoptotic proteins such as BAX and p53, leading to the induction of apoptosis in cells. Pasakbumin B also has been shown to decrease the viability of breast cancer cells by inhibiting their proliferation and increasing their sensitivity to chemotherapy treatments.
Pasakbumin B has not yet been studied for its safety in humans or animals.
Chemical properties
Technical inquiry about: 3D-NFA80910 Pasakbumin B
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