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[2'-18O]Guanosine
Ref. 3D-NG106386
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Product Information
Name:[2'-18O]Guanosine
Synonyms:
- 9-(b-D-[2-18O]Ribofuranosyl)guanine
Brand:Biosynth
Description:[2'-18O]Guanosine is a novel antiviral that has shown antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It also has anticancer effects, as it inhibits the growth of lymphoma cells by inhibiting DNA synthesis. [2'-18O]Guanosine is a modified nucleotide with an 18-oxygen atom in the 2' position, which prevents its use as a substrate for phosphodiesterases, thereby increasing its stability in vivo. [2'-18O]Guanosine is synthesized from the corresponding ribonucleotide, guanosine monophosphate (GMP), and can be used as an activator for DNA synthesis and an inhibitor of RNA synthesis.
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Chemical properties
Molecular weight:285.24 g/mol
Formula:C10H13N518OO4
Purity:Min. 95%
Technical inquiry about: [2'-18O]Guanosine
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