5-Hydroxycytidine

CAS: 39638-73-8

Ref. 3D-NH159404

Product Information

• Name: 5-Hydroxycytidine
• Synonyms: 5hoC
• Brand: Biosynth
• Description: 5-Hydroxycytidine is a pyrimidine nucleoside that is found in DNA and RNA. It can be produced by the conversion of cytidine 5-monophosphate to cytidine 5'-diphosphate, which is then hydrolyzed to produce 5-hydroxycytidine. This conversion requires the enzyme cytidylate kinase. The structure of 5-hydroxycytidine differs from other pyrimidine nucleosides as its hydroxyl group does not have an acidic proton present. Biological functions that have been attributed to 5-hydroxydihydrocytidylic acid include its ability to inhibit translation and induce cell death in lung cells. This compound has also been shown to modify DNA duplexes and form bioconjugates with proteins or small molecules, such as fluorescein and digoxigenin. These modifications are used in analytical methods such as phase chromatography, nuclear magnetic resonance spectroscopy

Chemical properties

• Molecular weight: 259.22 g/mol
• Formula: C₉H₁₃N₃O₆
• Purity: Min. 95 Area-%
• Color/Form: Powder