N6-Isobutyryl-2'-O-methyladenosine

Ref. 3D-NI08338

Product Information

• Name: N6-Isobutyryl-2'-O-methyladenosine
• Synonyms: N6-Isobutyryl-2'-O-methyl-D-adenosine
• Brand: Biosynth
• Description: N6-Isobutyryl-2'-O-methyladenosine is a nucleoside that has antiviral, anticancer, and anti-inflammatory properties. It is an analog of adenosine that is used in the synthesis of DNA and RNA. It is modified by the incorporation of an iso-butyl group at the 2' position on the ribose ring. N6-Isobutyryl-2'-O-methyladenosine was first synthesized in 1962 and has been extensively studied due to its novel properties. The phosphoramidites are activated with tetrazole or triazole, which are both strong activators. This nucleoside can be synthesized in high purity (>98%) through a modification of the conventional phosphorylation process.

Chemical properties

• Molecular weight: 351.36 g/mol
• Formula: C₁₅H₂₁N₅O₅
• Purity: Min. 95%
• InChI: InChI=1S/C15H21N5O5/c1-7(2)14(23)19-12-9-13(17-5-16-12)20(6-18-9)15-11(24-3)10(22)8(4-21)25-15/h5-8,10-11,15,21-22H,4H2,1-3H3,(H,16,17,19,23)/t8-,10+,11?,15-/m1/s1
• InChI key: InChIKey=IRXHRDQDJTWQAV-UENMMAHRSA-N
• SMILES: COC1[C@@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NC(=O)C(C)C)ncnc21