Product Information
Wy-135 is a potential drug that has shown inhibition of cyclin-dependent kinases. It has been shown to inhibit G1 phase cell cycle progression and induce apoptosis in a dose-dependent manner. Wy-135 has also been shown to inhibit the growth of cancer cells in culture. This compound may be useful as an anti-cancer agent and chemotherapeutic drug. Wy-135 inhibits cellular proliferation and induces apoptosis by inhibiting protein synthesis, DNA replication, and enzyme activity. The cocrystal structure of Wy-135 with cyclin was determined and its inhibitory activities were analyzed by cycle analysis. Wy-135's effects on cancer cells are due to its ability to inhibit the enzymatic activities involved in cell division, including protein synthesis and DNA replication.
Chemical properties
Technical inquiry about: 3D-NLD06083 WY-135
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