2'-O-Methyluridine

CAS: 2140-76-3

Ref. 3D-NM04259

Product Information

• Name: 2'-O-Methyluridine
• Synonyms: 2'-O-Methyl-D-uridine
• Brand: Biosynth
• Description: 2'-O-Methyluridine is a chemical compound that is used in the synthesis of RNA. It is an analog of uridine and has been shown to have antiviral and anticancer properties. 2'-O-Methyluridine inhibits protein synthesis by competing with uridine for the active site of the enzyme ribonucleotide reductase, which converts ribonucleotides to dNMPs. This compound also inhibits RNA synthesis by disrupting the pairing of adenine and cytosine residues in RNA strands. 2'-O-Methyluridine has been shown to inhibit growth in some types of cancer cells, including colorectal adenocarcinoma cells. It may also be useful as a chemotherapeutic agent against HIV, as it inhibits virus replication by inhibiting reverse transcription and DNA synthesis.

Chemical properties

• Molecular weight: 258.23 g/mol
• Formula: C₁₀H₁₄N₂O₆
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder