2'-O-Methyladenosine
CAS: 2140-79-6
Ref. 3D-NM05694
| 1g | 161.00 € | ||
| 2g | 209.00 € | ||
| 5g | 431.00 € | ||
| 10g | 655.00 € | ||
| 25g | 1,227.00 € |
Product Information
- 2'-O-Methyl-D-adenosine
- 2'-O-Methyl-adenosine
- 2'-OMe Adenosine
- Adenosine, 2'-O-methyl-
- Cordysinin B
2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.
Chemical properties
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