N7-Methylguanosine

CAS: 20244-86-4

Ref. 3D-NM08037

Product Information

• Name: N7-Methylguanosine
• Synonyms: 7-Methylguanosine 7-Methyl-7-hydroguanosine, 1H-Purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosyl-, 1H-Purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 2-Amino-6,9-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosyl-1H-purinium, 2-amino-7-methyl-9-beta-D-ribofuranosyl-7H-purin-9-ium-6-olate, Guanosine, 7-methyl-, N⁷-Methylguanosine, Purinium, 2-amino-1,6-dihydro-7-methyl-6-oxo-9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-

Description

N-7-Methylguanosine is a nucleotide that has potent anti-viral activity. It inhibits viral replication by binding to the effector proteins of a virus and preventing translation, transcriptional regulation, and other biochemical processes. N7-Methylguanosine also binds to the x-ray crystal structures of the viral genome and blocks the binding of RNA polymerase to DNA. This drug can be used as an antiviral agent for the treatment of HIV infection and hepatitis B infection. N7-Methylguanosine is not active against some viruses such as herpes simplex virus type 1 or 2, influenza virus type A/B, or rhinovirus type 2.
N7-Methylguanosine has been shown to have an effect on body mass index in humans by reducing weight gain in patients with metabolic syndrome. It also has an enzyme form that can be used for therapeutic use in human serum.

• Brand: Biosynth

Chemical properties

• Molecular weight: 297.27 g/mol
• Formula: C₁₁H₁₅N₅O₅
• Purity: Min. 95%
• Color/Form: White Powder