2-Methylthioadenosine 5-monophosphate
CAS: 22140-20-1
Ref. 3D-NM10203
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire |
Product Information
- Adenosine,2-(methylthio)-, 5'-(dihydrogen phosphate) (8CI)
- 2-MeSAMP
- 2-Methylthio-AMP
- 2-Methylthioadenosine 5'-monophosphate
- 2-Methylthioadenosine 5'-phosphate
2-Methylthioadenosine 5-monophosphate (2MTA) is an intermediate in purine metabolism that can be synthesized from adenosine monophosphate and methyl mercaptan. 2MTA inhibits the platelet aggregation by inhibiting the function of the P2Y12 receptor, which is a member of the G protein-coupled receptor family. It has been shown to inhibit tumor growth and tumor vasculature, as well as to induce apoptosis in cancer cells. 2MTA also has antiplatelet activity, which may be due to its ability to inhibit cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).
Chemical properties
Technical inquiry about: 3D-NM10203 2-Methylthioadenosine 5-monophosphate
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