Product Information
Name:8-Methylthioguanosine
Brand:Biosynth
Description:8-Methylthioguanosine is a purine nucleoside that is synthesized from guanosine by the enzyme nucleoside phosphorylase. 8-Methylthioguanosine is used in the treatment of leukemia cells and has been shown to have homogeneity, with a single peak on paper chromatography. It is also an inhibitor of purine nucleotide phosphorylase, which prevents the conversion of guanosine to inosine monophosphate and leads to depletion of intracellular ATP levels. This drug binds tightly to the active site of purine nucleotide phosphorylase and inhibits its activity. 8-Methylthioguanosine may be used as a radiosensitizer for cancer therapy and can be administered intravenously or orally.
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Chemical properties
Purity:Min. 95%
Technical inquiry about: 8-Methylthioguanosine
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