2-Methylthioadenosine-5'-triphosphate

CAS: 43170-89-4

Ref. 3D-NM72044

Product Information

• Name: 2-Methylthioadenosine-5'-triphosphate
• Synonyms: 2-MeS-ATP, 2-Methylthio-ATP, 2-Mesatp, 2-Methylthio-adenosine 5'-triphosphate, Mesatp cpd, Adenosine 5'-(tetrahydrogen triphosphate), 2-(methylthio)-, 2-(Methylsulfanyl)Adenosine 5'-(Tetrahydrogen Triphosphate)

Description

2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 553.27 g/mol
• Formula: C₁₁H₁₈N₅O₁₃P₃S
• Purity: Min. 95%