Product Information
- 1,N6-Ethenonicotinamide adenine dinucleotide1,N6-Etheno NAD
- Nicotinamide 1,N(6)-ethenoadenine dinucleotide
- 1,N(6)-Etheno-NAD
- Epsilon NAD
- Pyridinium, 3-(aminocarbonyl)-1-(5-O-(hydroxy(phosphonooxy)phosphinyl)-beta-D-ribofuranosyl)-, hydroxide, inner salt, 5'-5'-ester with 3-beta-D-ribofuranosyl-3H-imidazo(2,1-i)purine
- [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate
Nicotinamide 1,N6-ethenoadenine dinucleotide (NADH) is an enzyme form that binds to the active site of glutamate dehydrogenase (GDH). This binding prevents GDH from catalyzing the oxidation of NADH to NAD+, which is necessary for GDH activity. Nicotinamide 1,N6-ethenoadenine dinucleotide is a noncompetitive inhibitor that binds with a higher affinity than the substrate. It has been shown to be effective in inhibiting GDH in a model system and in enzyme preparations. The binding constant for nicotinamide 1,N6-ethenoadenine dinucleotide is 2 mM. The optimum pH for nicotinamide 1,N6-ethenoadenine dinucleotide activity is 6.8.
Chemical properties
Technical inquiry about: 3D-NN26196 Nicotinamide 1,N6-ethenoadenine dinucleotide
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