Product Information
- (4-methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine HCl
- 4-Quinazolinamine, 6-methoxy-N-(4-methoxyphenyl)-, hydrochloride (1:1)
- 6-Methoxy-N-(4-methoxyphenyl)quinazolin-4-amine hydrochloride (1:1)
Allosteric modulation of the dopamine receptor is a novel therapeutic approach to treat neurodegenerative disorders such as Parkinson's disease. Ly 456236 hydrochloride (LY456236) is an allosteric modulator that can regulate the activity of the D2 dopamine receptor by binding to an allosteric site. It has been shown to be neuroprotective in animal models and has clinical properties in humans. LY456236 does not bind to the glutamate or nicotinic acetylcholine receptors and does not cause locomotor activity or cholinergic symptoms. LY456236 also shows antidepressant effects, which may be due to its ability to regulate serotonin neurotransmission.
Chemical properties
Technical inquiry about: 3D-NNA73857 Ly 456236 hydrochloride
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