Product Information
Name:Niraparib hydrochloride
Brand:Biosynth
Description:Niraparib hydrochloride is an inhibitor of poly (ADP-ribose) polymerase, which is a key enzyme in the repair of DNA. It also inhibits the phosphorylation of histone H2AX at serine 139, which leads to cell cycle arrest and apoptosis. Niraparib hydrochloride has been shown to be effective against inflammatory lesions caused by radiation and platinum-resistant ovarian cancer. This drug has a synergistic effect with cisplatin in preclinical models for platinum-resistant ovarian cancer. Niraparib hydrochloride has also been evaluated as a potential biomarker for primary breast cancers by measuring its serum concentration in vivo using fluorescence imaging.
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Chemical properties
Molecular weight:356.85 g/mol
Formula:C19H21ClN4O
Purity:Min. 95%
Technical inquiry about: Niraparib hydrochloride
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