Product Information
Name:Sapacitabine
Synonyms:
- 1-(2-Deoxy-2-cyano-b-D-arabinofuranosyl)cytosine
Brand:Biosynth
Description:Sapacitabine is an oral prodrug that is converted to its active form, the cytotoxic agent 9-β-D-arabinofuranosyladenine (araA), by cellular enzymes. It has potent antitumor activity against solid tumours and has been shown to be effective in a variety of human cancer cell lines. Sapacitabine targets intracellular targets, including DNA methyltransferases and other enzymes involved in the synthesis of RNA and DNA. The drug has been shown to have synergistic effects when used with other cytotoxic agents such as 5-fluorouracil and gemcitabine, which are also inhibitors of DNA methyltransferase.
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Chemical properties
Molecular weight:490.64 g/mol
Formula:C26H42N4O5
Purity:Min. 95%
Technical inquiry about: Sapacitabine
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