2-Thiocytidine
CAS: 13239-97-9
Ref. 3D-NT02911
| 5mg | 106.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 386.00 € | ||
| 100mg | 486.00 € |
Product Information
- 2-Thio-D-cytidine dihydrate
- 2(1H)-Pyrimidinethione, 4-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 4-amino-1-beta-D-ribofuranosylpyrimidine-2(1H)-thione
- 4-amino-1-pentofuranosylpyrimidine-2(1H)-thione
- Cytidine, 2-thio-
2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.
Chemical properties
Technical inquiry about: 3D-NT02911 2-Thiocytidine
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