4-Thiothymidine
CAS: 7236-57-9
Ref. 3D-NT06341
| 1g | 478.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 170.00 € | ||
| 250mg | 261.00 € | ||
| 500mg | 369.00 € |
Product Information
- 4-Thio-D-thymidine
- 1-(2-deoxypentofuranosyl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
- Thymidine, 4-thio-
4-Thiothymidine is a nucleoside analog that is converted to thymidine by the enzyme thymidine kinase. It has been shown to inhibit the growth of human skin cancer cells by binding to DNA duplexes and inhibiting the synthesis of new DNA strands. 4-Thiothymidine has also been shown to be effective against radiation-induced damage in cultured human cells and inhibits tumor growth in mice bearing a transplantable mouse skin cancer. 4-Thiothymidine can be used as an inhibitor for chemotherapy or radiation therapy for cancer patients. It is active on both site-specific and cell-specific gene targets, with a reactive hydrogen bond that helps stabilize its formation.
Chemical properties
Technical inquiry about: 3D-NT06341 4-Thiothymidine
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