5'-O-Tosylthymidine

CAS: 7253-19-2

Ref. 3D-NT10016

Product Information

• Name: 5'-O-Tosylthymidine
• Synonyms: 5'-O-Tosyl-D-thymidine
• Brand: Biosynth
• Description: 5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.

Chemical properties

• Molecular weight: 396.42 g/mol
• Formula: C₁₇H₂₀N₂O₇S
• Purity: Min. 95%