6-Thioinosine 5'-monophosphate

CAS: 53-83-8

Ref. 3D-NT10843

Product Information

• Name: 6-Thioinosine 5'-monophosphate
• Brand: Biosynth

Description

6-Thioinosine 5'-monophosphate (6TIMP) is a hydrogen bond donor that possesses inhibitory properties against protein synthesis. It has been shown to have an anti-inflammatory effect and can be used for the treatment of inflammatory bowel disease. 6TIMP is also able to inhibit the bcr-abl kinase, which is implicated in the development of renal cell cancer. 6TIMP can be administered intravenously or orally and penetrates tissues well. The rate at which it enters cells is dependent on the transport rate, which is determined by its acidity. 6TIMP has been shown to cause DNA damage, leading to apoptosis and cell death in carcinoma cell lines. The mechanism of action appears to involve inhibition of cellular protein synthesis, acid formation, and DNA damage.

Chemical properties

• Molecular weight: 364.27 g/mol
• Formula: C₁₀H₁₃N₄O₇PS
• Purity: Min. 95%
• Color/Form: Powder