Toyocamycin monohydrate

CAS: 58151-27-2

Ref. 3D-NT44985

Product Information

• Name: Toyocamycin monohydrate
• Synonyms: 4-Amino-5-cyano-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidineVengicide7-Deaza-7-cyanoadenosine7-Cyano-7-deazaadenosine
• Brand: Biosynth
• Description: Toyocamycin is a macrolide antibiotic that inhibits protein synthesis by binding to the 50S ribosomal subunit. Toyocamycin monohydrate (TM) has been shown to have significant cytotoxicity against HL-60 cells, which may be due to its ability to inhibit mitochondrial membrane potential and induce apoptosis. The drug also has inhibitory properties against wild-type strains of bacteria, such as diastatochromogenes, and is active against high-resistant strains of bacteria, such as E. coli. Toyocamycin monohydrate has been shown to inhibit transcriptional regulation in hl-60 cells and k562 cells by binding to RNA polymerase II and blocking RNA synthesis.

Chemical properties

• Molecular weight: 309.28 g/mol
• Formula: C₁₂H₁₃N₅O₄•H₂O
• Purity: Min. 95%
• Color/Form: White Powder