Toyocamycin monohydrate
CAS: 58151-27-2
Ref. 3D-NT44985
| 5mg | 144.00 € | ||
| 10mg | 206.00 € | ||
| 25mg | 356.00 € | ||
| 50mg | 497.00 € | ||
| 100mg | 775.00 € |
Product Information
- 4-Amino-5-cyano-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidineVengicide7-Deaza-7-cyanoadenosine7-Cyano-7-deazaadenosine
Toyocamycin is a macrolide antibiotic that inhibits protein synthesis by binding to the 50S ribosomal subunit. Toyocamycin monohydrate (TM) has been shown to have significant cytotoxicity against HL-60 cells, which may be due to its ability to inhibit mitochondrial membrane potential and induce apoptosis. The drug also has inhibitory properties against wild-type strains of bacteria, such as diastatochromogenes, and is active against high-resistant strains of bacteria, such as E. coli. Toyocamycin monohydrate has been shown to inhibit transcriptional regulation in hl-60 cells and k562 cells by binding to RNA polymerase II and blocking RNA synthesis.
Chemical properties
Technical inquiry about: 3D-NT44985 Toyocamycin monohydrate
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