Product Information
Name:VU0486846
Brand:Biosynth
Description:VU0486846 is a novel, non-competitive, allosteric modulator of nicotinic acetylcholine receptors. It is a potent inhibitor of the high-affinity choline uptake system and prevents the accumulation of acetylcholine in tissues. VU0486846 has shown efficacy in preclinical models in which it was able to enhance responsiveness to acetylcholine. As an allosteric modulator, VU0486846 binds to a different site on the receptor than acetylcholine, and thereby reduces the number of acetylcholine molecules required for activation. This pharmacokinetic profile could potentially allow for lower doses of this drug to be administered, with fewer side effects.
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Chemical properties
Molecular weight:432.5 g/mol
Formula:C25H28N4O3
Purity:Min. 95%
Technical inquiry about: VU0486846
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